11 08 19

first_imgWorld Travel Market 2016, ExCeL, London –The travel tech show.World Travel Market 2016, ExCeL London – Bloggers speed networking.World Travel Market 2016, ExCeL, London. Tourism ministers, bloggers and party goers turned the final day of the revamped three-day WTM London into a festival of business and fun.The UNWTO & WTM Ministers’ Summit is one of the highest-profile sessions of the entire event. Now in its 10th year, more than 100 tourism ministers and their aides from around the world were joined by board-level representatives from some of the biggest travel companies.This year’s Summit called on the industry and governments to work together to help destinations cope with the threat of terrorism, which UNWTO Secretary-General Dr Taleb Rifai described as “forces of darkness”.Mohamed Yehia Rashed Tourism Minister Egypt assured delegates that his country has the technology and security measures in place to protect tourists and urged for standard security measures to be introduced globally. Vinod Zutshi, Secretary of Tourism in the government of India – WTM London’s Official Premier Partner – said countries needed to be more responsible when issuing travel advisories as perception of safety in destinations is a key factor.Zutshi’s call was echoed by Fritz Joussen, Chief Executive TUI Group, who noted people’s perceptions often compound the problems of terrorism. “The probability of being killed by a terrorist is lower than having car accident on the way to the airport,” he said.As the leading global event for the travel industry, WTM London welcomes all levels of participants in the business, from ministers to bloggers. At a dedicated Speed Networking event, 100 bloggers from 15 different countries talked to exhibitors interested in using this increasingly important channel.Valentina Correa, based in Germany but originally from Colombia, runs www.unpocodesur.com, an adventure blog. “We have relationships with tour operators but WTM is a fantastic chance to talk to tourist boards and hotels as we look to widen our coverage. It is a great chance too to educate some of the exhibitors about the benefits of working with bloggers.”WTM London is now applying its highly successful speed networking concept to new verticals, with a dedicated wellness session also taking place today. Lisa Wakefield Programme Leader University of Derby said: “We run International Tourism and Spa Management degrees and courses in hospitality, the culinary arts and event management and I’ve managed to talk to lots of businesses about taking our students on placement.”While spa speed networking is new, Richard Cope Senior Trends Consultant Mintel is a WTM London regular. Attendees at his well-attended session were given first access to its 2017 consumer trends analysis, getting advance notice on wearables as a payments device, travel brands sponsoring the restoration of iconic monuments across Europe, chatbots and AI becoming a mainstream customer service channel and the potential time-limited offers and promotions.Elsewhere Mexico City Tourism Trust Director Magdalena Sanchez noted that Donald Trump’s victory in the US election came on the 27th anniversary of the day the Berlin Wall came down. “The most important thing is to say Mexico is open for business to the world. As a tourist service we are working to strengthen our markets, this is why we are here,”Simon Press, Senior Director, WTM London 2016 said: “Our decision to revamp WTM London as a three-day event was in response to our listening and responding to our core audience of buyers, exhibitors and visitors. We are confident we have, yet again, delivered a best-in-class event which reconfirms our status as the leading global event for the travel industry.”last_img read more

20 07 19

first_imgMay 16 2018Cleveland Clinic researchers have demonstrated for the first time that lowering blood cholesterol levels could enhance the success of a specific type of T-cell immunotherapy in fighting cancer.The team, led by Qing Yi, MD, PhD, of Cleveland Clinic Lerner Research Institute studied T-cell transfer, which has shown great success in recent years. Dr. Yi previously showed that a specific subset of T-cells, called Tc9 cells, have stronger anti-tumor effects than other types of T-cells. In the newly published study, they determined the mechanisms that give Tc9 cells their anti-cancer properties and how those mechanisms might be tweaked to enhance immunotherapy.Related StoriesNew protein target for deadly ovarian cancerAdding immunotherapy after initial treatment improves survival in metastatic NSCLC patientsStudy reveals link between inflammatory diet and colorectal cancer riskUsing gene profiling, the researchers discovered that Tc9 cells had much lower levels of intracellular cholesterol than other T-cells. They hypothesized that the reduced cholesterol levels might contribute to the cells’ anti-tumor effects. Indeed, when cholesterol-lowering drugs were administered to the cells, anti-cancer pathways were turned on (IL-9 expression and NF-KB signaling). Furthermore, they showed in a tumor-bearing preclinical model that reducing cholesterol levels prior to immunotherapy led to greater concentrations of IL-9 and better cancer-killing success.Immunotherapy is a type of cancer treatment that harnesses the power of the human immune system to attack and kill cancer cells. Adoptive T-cell transfer involves transplanting T-cells engineered to recognize a certain type of cancer. Researchers have focused on many different methods to manipulate and enhance the T-cells’ anti-cancer activity, such as transferring cells at different stages of differentiation or using certain drugs in tandem with immunotherapy.”Our studies suggest a relatively simple, cost effective way to enhance T-cell transfer therapy,” Dr. Yi said. “We hope to test our findings in clinical trials soon.” Source:https://my.clevelandclinic.org/last_img read more